Editor’s note: The University of Illinois Veterinary Teaching Hospital is a sponsor of Chambanamoms.com.
By Dr. Canaan Shores, University of Illinois Veterinary Medicine
Jelly, a handsome young Ragdoll cat, was in trouble. His owner, recently home from a trip, had noticed him straining in the litter box. In keeping with his mysterious feline persona, Jelly’s problem was enigmatic. And no way was Jelly telling his secrets!
After careful evaluation, it was apparent that Jelly was in distress and his issue wasn’t going to resolve itself without intervention. Jelly’s owner rounded up the cat carrier, loaded him in, and brought him to University of Illinois’ Urgent and Convenient Care Service.

After discussing his clinical signs (the veterinary word for “symptoms”) and running some basic tests, we diagnosed Jelly with a condition called feline idiopathic cystitis (FIC).
Understanding FIC: A Common and Frustrating Condition
Feline idiopathic cystitis is one of the most common causes of lower urinary tract disease in cats. Characterized by inflammation of the bladder without an identifiable cause, FIC can be distressing for both cats and their owners. While not always dangerous, it has the potential to become life-threatening in male cats if a urethral obstruction develops.
Who Is at Risk?
FIC most commonly affects young to middle-aged, neutered indoor cats, particularly those living in multi-cat households. Stress plays a significant role in triggering or exacerbating the condition. Overweight or obese cats and those with low water intake are also at increased risk. There is no known breed predisposition, but males are more vulnerable to complications due to their narrower urethras.

Clinical Signs
The clinical signs of FIC are often mistaken for a urinary tract infection because FIC causes inflammation of the bladder. However, in FIC, no infection is present. Signs may include:
- Frequent trips to the litter box (pollakiuria)
- Straining to urinate (stranguria)
- Blood in the urine (hematuria)
- Urinating outside the litter box
- Vocalizing while urinating
- Excessive grooming of the genital area
These signs may appear suddenly and can resolve on their own within 5 to 7 days, even without treatment. However, recurrence is common.
Treatment
There is no single cure for FIC, but management focuses on reducing inflammation, pain, and stress while promoting healthy urinary habits.
Key components of treatment include:
- Pain control: NSAIDs, opioids, and/or gabapentin may be prescribed during flare-ups.
- Environmental enrichment: Reducing stress is crucial. This includes offering hiding spots, vertical spaces, interactive play, and maintaining consistent routines.
- Dietary management: Feeding canned food or switching to urinary-formulated diets can help increase water intake and reduce urine concentration.
- Increased hydration: Encouraging water consumption through fountains or multiple water bowls can dilute urine and reduce bladder irritation.
- Litter box hygiene: Clean, easily accessible, and well-placed litter boxes (one per cat, plus one extra) reduce stress and encourage normal urination.
Behavioral modification or anti-anxiety medications (e.g., fluoxetine) may be considered in recurrent cases.

Prevention
Since FIC tends to recur, preventive management is vital:
- Minimize household stressors (e.g., new pets, loud noises, or changes in routine)
- Encourage hydration and a high-moisture diet
- Maintain a clean and accessible litter box setup
- Provide predictable schedules and enriched environments
Monitoring for early signs of recurrence allows for prompt intervention.
A Word on Urethral Obstruction
One of the most serious complications of FIC is urethral obstruction, which most often affects male cats due to their narrow urethras. (At its most narrow point, the urethra of a male cat can be the same diameter as the ball in a ballpoint pen!)
Urethral obstruction occurs when inflammation and muscle spasms, or urethral plugs, block urine flow.
Signs of obstruction include:
- Repeated straining with no urine output
- Vocalizing in pain
- Lethargy, vomiting, or collapse
Urethral obstruction is a medical emergency. Without prompt treatment, it can lead to kidney failure, electrolyte imbalances, and death within 24 to 72 hours. Any cat suspected of being unable to urinate should be taken to a veterinarian immediately.
Final Thoughts
Feline idiopathic cystitis is a complex, frustrating condition, but with the right management strategies, many cats can live comfortable, healthy lives. Recognizing signs early, reducing environmental stress, and promoting hydration are key to both treatment and prevention.
So, what became of Jelly? His symptoms began to improve within 24 hours, and he’s much better now. However, his owner will monitor for any recurrence and follow up with his primary care veterinarian if problems arise.
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The University of Illinois Veterinary Teaching Hospital offers a full range of emergency, specialty, urgent, and primary care for dogs and cats, horses, zoological companion animals, and farm animals within its Large and Small Animal Clinics and Veterinary Medicine South Clinic.
The Urgent and Convenient Care service, led by Dr. Canaan Shores, is located in the South Clinic, 2100 South Goodwin Avenue, Urbana, across Hazelwood Drive from the Large and Small Animal Clinics. The Urgent and Convenient Care service sees dogs and cats. Its hours are Monday through Friday, 10 a.m. to 6 p.m.
Call (217) 244-2555 if you need to see the urgent care veterinarian.



